1) Brandon LaFell (Pats)
The Eagles have given up 5 TD passes a piece the last two weeks to Jameis Winston and Matt Stafford. Now they face a Tom Brady coming off his first loss of the season. No Gronk. No Edelman. No Amendola. Just Brandon LaFell.

2) Amari Cooper (Oak)
The Chief has given up the 2nd most fantasy points to WR David Carr with his new best friend. Cooper will take over this AFC west battle and make this secondary pay.

3) Antonio Brown (Pitt)
With the Steeler WR Markus Wheaton going off last week with over 200yds vs the Legion of Boom Big Ben will find Brown all night vs the Colts in this must win match up for Pittsburgh.